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All patients had New York Heart Association class II, III, or IV symptoms. All individuals who experienced undergone implantation based on these criteria in France and Monaco since 2010 were prospectively contained in the registry, without the use of exclusion criteria. The French Aortic National CoreValve and Edwards Registry was established under the French Societies of Cardiology and of Thoracic and Cardiovascular Operation. Personnel at all centers underwent structured training. Supervisors monitored situations at each new organization until they were self-confident that clinicians had acquired sufficient expertise to execute secure independent implantation. Four centers were in the training phase, and the first procedures were supervised; the others had already each performed a lot more than five procedures.