Surprisingly, the pattern of restriction-enzyme digestion didn’t match that anticipated for HPV-11 . All the indicated restriction enzymes should slice the viral DNA once to create a linearized genome of 7931 foundation pairs .6 Instead, these enzymes twice slice the DNA, generating fragments of about 8 kb and 2 kb. In addition, the size of the viral genome was estimated to become more than 10 kb when it had been linearized by HindIII, XbaI, or SphI. This suggested potential duplication of the L1-LCR-E6-E7-E1 region. To help expand evaluate this possibility, we cloned the viral genome into the vector pUC19 and sequenced it from two directions. According to sequencing data, the mutant HPV-11 genome included 10,424 bp due to duplication of 2493 bp that include partial L1-LCR-E6-E7-partial E1 sequences .A new study by Douglas Institute researchers unravels a feasible basis for these perturbations. First study showing function of clock genes in multiple areas of the human human brain As yet, the genes contributing to this timing, referred to as time clock genes, have only been found to become active in areas beyond your brain, like the skin and blood cells. Recent findings from the Douglas Mental Health University Institute are the first to present these genes function in multiple areas of the human mind as well, as was demonstrated previously in animals.